The academic program of Muskingum University operates on the assumption that learning is advanced by regular attendance at class and laboratory.

New first-year students are assigned to faculty or staff advisors through the First-Year Program. These advisors provide counsel and assistance in academic and social acclimation and arranging course schedules. Students are required to declare a major no later than the middle of the second semester of their sophomore year. Once a student declares a major, he/she is then reassigned to a faculty advisor who teaches in that major.