Instructor:

Dr. Brian P. Bergstrom

Office: SC 431

Office Hours: MWF 9:00-11:00

Room: SC439, 9:30AM-10:50 AM TTH(lecture), SC439, 12:30PM-3:20PM W(laboratory)

Phone: 8225 Email: Brianb@muskingum.edu

Instructor Home page: http://fates.cns.muskingum.edu/~brianb

Course Objective:

This course is designed to illustrate the comprehensive physiology of cells. Classical courses in cell physiology are grounded in biophysics, unfortunately, this can limit the scope of the subject matter. Therefore, the majority of this course will rely upon topics from biophysics, biochemistry, and cellular & molecular biology. Cell physiology is an exciting field of biology that incorporates many diverse fields and requires one to cross scientific boundaries and think between the lines. The laboratory portion of the course will focus on membrane biophysics, cell fractionation, protein assay, enzyme kinetics, immunofluorescence, and neurophysiology. Upon successful completion of this course, students will have a thorough understanding of cell function and the major techniques used in modern research laboratories.

Textbooks: Molecular Cell Biology 5^th Ed., Lodish et al., W.H. Freeman & Co., New York, NY.

Lecture/Exam Schedule

Week: Topic

1/8 Intro/ Dynamic Cell (Chpt.1)

1/15 No Class Mon.Chem. Found /Proteins (Chpts. 2,3)

1/22 Proteins cont./Protein Sorting (Chpts. 3, 17)

1/29 Protein Sorting/Macromolecule Synthesis (Chpts. 17,4) EXAM 1 (2/5)

2/5 Macromolecule Synthesis/Biomembranes (Chpts. 4, 5)

2/112 Biomembranes cont./Membrane Transport (Chpts. 5, 15)

2/19 Membrane Transport cont./Nerve Cells (Chpts. 15, 21)

2/26 Nerve Cells cont. (Chpt. 21) EXAM 2 (3/2)

3/5 Spring Break

3/12 Integrating Cells into Tissues (Chpt. 22)

3/19 Tissues cont./ Cell Interactions in Development (Chpts. 22, 23)

3/26 Cell Interactions in Development (Chpt. 23)

4/2 Cancer (Chpt. 24) EXAM 3 (4/3); No class 4/5

4/9 Cell Motility I (Chpt. 18)

4/16 Cell Motility II (Chpt. 19)

4/23 Cell to Cell Signaling (Chpt. 20)

4/27 Final Exam 12 noon

Grading:

Your final grade will be calculated from the lecture and laboratory portions of the course. There will be four lecture exams that will be equally weighted (15%). The fourth exam will be taken during the week of final examinations. The laboratory will be worth 30% and is described in a separate syllabus. The remaining 10% will come from required written assignments.

Attendance Policy: At this point in your studies, it is your sole responsibility to come to the lecture and laboratory. Absences in a course of this stature are self-limiting on academic performance.

Note: Alterations to this syllabus can and may be made at the discretion of the instructor.