Lecture 9: Protein Sorting: Organelle Biogenesis and Protein Secretion
17.5 A single internal topogenic sequence directs insertion of some single-pass transmembrane proteins
17.5 Multipass transmembrane proteins have multiple topogenic sequences
17.5 After insertion into the ER membrane, some proteins are transferred to a GPI anchor
17.6 Post-translational modifications and quality control in the rough ER
17.6 Disulfide bonds are formed and rearranged in the ER lumen
17.6 Correct folding of newly made proteins is facilitated by several ER proteins
17.6 Only properly folded proteins are transported from the rough ER to the Golgi
17.6 ER-resident proteins often are retrieved from the cis-Golgi
17.7 Different structures characterize N- and O-linked oligosaccharides
17.7 Specific sugars are linked by specific glycosyltransferases
17.7 ABO blood type is determined by two glycosyltransferases
17.7 ABO blood groups
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