Lecture 7: Protein Sorting: Organelle Biogenesis and Protein Secretion

02/13/2002


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Table of Contents

Lecture 7: Protein Sorting: Organelle Biogenesis and Protein Secretion

17.0 Overview of sorting of nuclear-encoded proteins in eukaryotic cells

17.1 Specific uptake-targeting sequences in newly made proteins are recognized by different organelles

17.1 Most mitochondrial proteins are synthesized as precursors containing uptake-targeting sequences

17.1 Uptake-targeting sequences of imported mitochondrial proteins

17.1 Cytosolic chaperones deliver proteins to channel- linked receptors in the mitochondrial membrane

17.1 Studies with chimeric proteins confirm major features of mitochondrial import

17.1 Proteins are targeted to submitochondrial compartments by multiple signals and several pathways

17.2 C- and N-terminal targeting sequences direct entry of folded proteins into the peroxisomal matrix

Author: Brian Bergstrom

Email: Brianb@muskingum.edu

Home Page: http://muskingum.edu/~brianb/Cellphys/Cellphys.html