Lecture 4: Protein Structure & Function
3.1 Protein structure determines function
3.1 All amino acids have the same general structure but the side chain (R group) of each is different
3.1 Hydrophilic amino acids
3.1 Hydrophobic and “special” amino acids
3.1 Peptide bonds connect amino acids into linear chains
3.1 Four levels of structure determine the shape of proteins
3.1 Primary and secondary structure in hemagglutinin
3.1 Tertiary and quaternary structure in hemagglutinin
3.1 Different graphical representations of the same protein
3.1 Secondary structure: the ? helix
3.1 Secondary structure: the beta sheet
3.1 Motifs
3.1 Other examples of motifs
3.1 Structural and functional domains are modules of tertiary structure
3.1 Sequence homology suggests functional and evolutionary relationships between proteins
3.2 Folding, modification, and degradation of proteins
3.2 The information for protein folding is encoded in the sequence
3.2 Folding of proteins in vivo is promoted by chaperones
Email: Brianb@muskingum.edu
Home Page: http://muskingum.edu/~brianb/Cellphys/Cellphys.html